AIDS is said______the biggest health challenge to both men and women in that area over the past few years.

A.that it is                           B.to be

C.that it has been                  D.to have been

D


解析:

根據(jù)時間狀語“over the past few years”可判斷出要用“動詞+ing”形式的完成式，表示動作發(fā)生在謂語動詞之前。

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